El abordaje especulativo de los problemas artísticos realizado por el philosophe Denis Diderot (1713-1784) a lo largo de su carrera, desde sus tempranos Pensamientos filosóficos (1746) hasta El sobrino de Rameau –obra póstuma que fascinó a Goethe– ha sido objeto de estudio de una bibliografía vastísima, algunas de cuyas tesis no dejan de sorprender al estudioso: no tanto por el carácter original o provocativo que presentan sino por el mucho más simple hecho de que, a menudo, suelen contradecirse entre sí.Esto (...) resulta evidente cuando se revisa el modo en que nuestro autor, en consonancia con las preocupaciones epocales, concibe y elabora la relación entre las artes particulares, específicamente, entre la pintura y la poesía. En efecto –y aquí está lo que nos ha llamado la atención en nuestra investigación– críticos e historiadores del arte y de la literatura que han abordado desde una perspectiva histórica y teórica las implicancias del tópico ut pictura poesis en la tradición estética occidental toman frente a Diderot. (shrink)

In the literature on medical ethics, it is generally admitted that vulnerable persons or groups deserve special attention, care or protection. One can define vulnerable persons as those having a greater likelihood of being wronged – that is, of being denied adequate satisfaction of certain legitimate claims. The conjunction of these two points entails what we call the Special Protection Thesis. It asserts that persons with a greater likelihood of being denied adequate satisfaction of their legitimate claims deserve special attention, (...) care or protection. Such a thesis remains vague, however, as long as we do not know what legitimate claims are. This article aims at dispelling this vagueness by exploring what claims we have in relation to health care – thus fleshing out a claim-based conception of vulnerability. We argue that the Special Protection Thesis must be enriched as follows: If individual or group X has a greater likelihood of being denied adequate satisfaction of some of their legitimate claims to physical integrity, autonomy, freedom, social provision, impartial quality of government, social bases of self-respect or communal belonging, then X deserves special attention, care or protection. With this improved understanding of vulnerability, vulnerability talk in healthcare ethics can escape vagueness and serve as an adequate basis for practice. (shrink)

¿Es posible que el arte progrese al mismo ritmo que la filosofía racional? ¿No existe algún tipo de incompatibilidad constitutiva entre ambos modos de interpretar la realidad, de manera tal que, siempre, la mayor precisión de la última implica una menor intensidad del primero? Tales preguntas constituyeron un vital eje de preocupación para los pensadores de la Ilustración francesa. En este artículo, nos concentramos en la respuesta que Denis Diderot intenta dar al dilema. Mostramos, en primer lugar, cómo el editor (...) de la Encyclopédie diferencia ambas áreas de la producción humana a la hora de trazar su historia: si bien es necesario destacar el progreso de la razón, lo es también el reconocer la decadencia de las artes como una de sus consecuencias. En segundo lugar, mostramos cómo, elaborado este diagnóstico, Diderot procura, a través de propuestas pictóricas, poetológicas y dramatúrgicas, salvar la potencia estética del arte para un siglo ilustrado. (shrink)

Vulnerability has been extensively discussed in medical research, but less so in health care. Thus, who the vulnerable in this domain are still remains an open question. One difficulty in their identification is due to the general criticism that vulnerability is not a property of only some, but rather of everyone. By presenting a philosophical analysis of the conditions of vulnerability ascription, we show that these seemingly irreconcilable understandings of vulnerability are not contradictory. Rather, they are interdependent: they refer to (...) the same concept with different likelihoods of manifestation. We argue that the general vulnerability of living beings relies on their having certain types of interests. In health care, those individuals are particularly vulnerable who are more likely to have these interests unjustly considered. They should be afforded special protection in order to receive what is due to everyone, but which they are likely to fail to receive. (shrink)

We discuss ethical aspects of risk-taking with special focus on principlism and mid-level moral principles. A new distinction between the strength of an obligation and the degree to which it is valid is proposed. We then use this distinction for arguing that, in cases where mid-level moral principles come into conflict, the moral status of the act under consideration may be indeterminate, in a sense rendered precise in the paper. We apply this thought to issues related to pandemic influenza vaccines. (...) The main conclusion of the paper is that on a principlist approach some acts may be neither right nor wrong (or neither permissible nor impermissible), and we claim that this has important implications for how we ought to make decisions under risk. (shrink)

Intellectual property has traditionally been a matter for the legal professions, but with the shift to evidence-based policy, the global economic upheaval, and the advent of the digital age, intellectual property is increasingly informed by economic perspectives. This book is a comprehensive, critical analysis of economic interpretations of intellectual property, written for researchers, practitioners and policymakers. It analyses the interface between economics, finance, accountancy and intellectual property law. Commencing with a critical analysis of the economics of innovation, law, industrial organisation (...) and welfare, the book then critiques the economics of specific intellectual property rights, including copyright, patents, trade marks, geographical indications and design rights. It further assesses the interaction between economics, IP and competition. Finally, it examines why, when and how IP generates value, reviewing contemporary approaches to valuation and accounting, and the emerging use of IP to facilitate business finance. This analytical text offers readers a better understanding of IP's contribution to macro- and microeconomics, as well as insights that inform the debate on evidence-based IP policy. (shrink)

In his reflections on the spatiotemporal structuring of the life-world, Schütz distinguishes between two forms of intersubjectivity among contemporaries. Firstly, he points at actors sharing both space and time and experiencing a direct, immediate face-to-face communication; secondly, he indicates the intersubjectivity of indirect communication, lacking any commonalities of space and time, such as the correspondence by letter. Apart from the strict exchange of thoughts, the alternating writing gives one the chance to relate to the interpretive patterns and relevancies of the (...) correspondent and thereby to understand more clearly the intellectual position of the proponent. Reflecting on the specificity of the situation, Schütz claims: “The written communication forced upon us by the geographical distance between us should at least have the benefit of encouraging us to put our thoughts, as best we can, into a clear and orderly form” (p. 49). The correspondence between Alfred Schütz and Eri. (shrink)

En este trabajo partimos de la hipótesis de que Heidegger tiene en miras las nociones aristotélicas de _δύναμις_ (_dýnamis_) y _δυνατóν_ (_dynatón_) al momento de tematizar su concepto de posibilidad (_Möglichkeit_) en _Sein und Zeit_ (1927), pero no con el sólo propósito de asimilar las reseñadas conceptualizaciones –apropiación que, como veremos subsiguientemente, no es plena-, sino también, para radicalizarlas, asumiendo un punto de vista francamente superador. Sustentamos esta tesis, en principio, en el hecho que Aristóteles haya pensado que la _ἐνέργεια_ (...) (_enérgeia_) o _ἐντελέχεια_ (_entelécheia_) es, en términos generales, anterior (_πρότερον_/_próteron_) respecto de la _dýnamis_, siendo esta posición teórica revisada y renovada por Heidegger en el texto reseñado. Por otra parte, Heidegger cuestiona la tesis aristotélica de la fundamentalidad de la realidad efectiva (_Wirklichkeit_) o de la realidad a secas (_Realität_) y como consecuencia de ello, el concepto aristotélico de ser (_εἶναι/eînai_), _ἐστίν_ (_estín_) o lo que es (_ὄν/ón_), señalando no sólo que la posibilidad es más originaria que la realidad efectiva, sino también, que la realización de una posibilidad no implica nunca la transición a una realidad efectiva. Además, el vínculo de Heidegger con Aristóteles se inicia muy tempranamente -más específicamente, en el año 1907-, merced a la lectura de la tesis doctoral de Franz Brentano y se prolonga constantemente desde 1921, cuando Heidegger dicte un seminario sobre _De Anima_ en la Universidad de Friburgo. (shrink)

Intellectual property has traditionally been a matter for the legal professions, but with the shift to evidence-based policy, the global economic upheaval, and the advent of the digital age, intellectual property is increasingly informed by economic perspectives. This book provides a clear and practical guide to economic approaches to intellectual property, written for a legal audience. It introduces basic concepts in economics and finance that inform the law of intellectual property. Topics discussed offer additional perspectives include the economics of innovation, (...) development, crime, law, industrial organisation and welfare. Next, it considers the economics of specific intellectual property rights, including copyright, patents, trademarks, trade secrets, geographical indicator and design rights, as well as a section on competition. Finally, a section on applied approaches to the valuation of IP will help readers to understand the use of these topics in practice.This practical text offers readers a better understanding of economic debates in intellectual property, as well as tools to enhance their ability to critique evidence-based policy. (shrink)

The contention of this paper is that the current ethical debate over embryonic stem cell research is polarised to an extent that is not warranted by the underlying ethical conflict. It is argued that the ethical debate can be rendered more nuanced, and less polarised, by introducing non-binary notions of moral rightness and wrongness. According to the view proposed, embryonic stem cell research—and possibly other controversial activities too—can be considered ‘a little bit right and a little bit wrong’. If this (...) idea were to become widely accepted, the ethical debate would, for conceptual reasons, become less polarised. (shrink)

One of the high-points of Italian Renaissance humanism, Machiavelli's The Prince immediately transcended the time and culture from which it had sprung, circulating throughout Europe and paving the road to an astonishing variety of discussions on power and liberty for centuries to come. Indeed, one could hardly think of a literary work whose reception has been more controversial and arguably more crucial to the fashioning of modernity. This volume gathers together the proceedings of a conference held in Oxford, in November (...) 2013, to mark the 500th anniversary of the composition of The Prince. It explores pivotal aspects of the text's complex identity, focusing on three interrelated areas: 1. The Prince's own ways of appropriating ancient and modern traditions of political thought and ethics; 2. the textual history and interpretive details of the work; 3. translations of the treatise into foreign languages (including English and other translations), with their cultural adaptations and reconceptualizations of the original. All chapters offer highly original insights by leading experts on The Prince, shedding light on hitherto neglected topics and locating Machiavelli's masterpiece in an intriguing network of intersecting perspectives. (shrink)

In the present work, we raise the question of the elaboration of an ethical and political praxis in the era of precariousness. We postulate a division intrinsic to the subject immersed in the neoliberal capitalism, whilst arguing for the continuity of said subjectivity with the ethical developments of Kant, through the resignification of its emancipatory components. We sustain that identity politics are insufficient as a means to overcome the ethics of precariousness insofar as they fail to articulate an idea of (...) universality. Against them, we argue in favor of R. Negarestani’s position about the labor that supposes the construction of a new rationality and we evaluate said project through the concept of value, necessary to conceive an alternative to an intrinsically economical order. (shrink)

For years, phenomenological psychiatry has proposed that distortions of the temporal structure of consciousness contribute to the abnormal experiences described before schizophrenia emerges, and may relate to basic disturbances in consciousness of the self. However, considering that temporality refers mainly to an implicit aspect of our relationship with the world, disturbances in the temporal structure of consciousness remain difficult to access. Nonetheless, previous studies have shown a correlation between self disorders and the automatic ability to expect an event in time, (...) suggesting timing is a key issue for the psychopathology of schizophrenia. Timing disorders may represent a target for cognitive remediation, but this requires that disorders can be demonstrated at an individual level. Since cognitive impairments in patients with schizophrenia are discrete, and there is no standardized timing exploration, we focused on timing impairments suggested to be related to self disorders. We present the case report of AF, a 22 year old man suffering from schizophrenia, with no antipsychotic intake. Although AF shows few positive and negative symptoms and has a normal neurocognitive assessment, he shows a high level of disturbance of Minimal Self Disorders (SDs) (assessed with the EASE scale). Moreover, AF has a rare ability to describe his self and time difficulties. An objective assessment of timing ability (variable foreperiod task) confirmed that AF had temporal impairments similar to those previously described in patients, i.e., a preserved ability to distinguish time intervals, but a difficulty to benefit from the passage of time to expect a visual stimulus. He presents additional difficulties in benefitting from temporal cues and adapting to changes in time delays. The impairments were ample enough to yield significant effects with analyses at the individual level. Although causal relationships between subjective and objective impairments cannot be established, the results show that exploring timing deficits at the individual level is possible in patients with schizophrenia. Besides, the results are consistent with hypotheses relating minimal self disorders (SDs) to timing difficulties. They suggest that both subjective and objective timing investigations should be developed further so that their use at an individual level can be generalized in clinical practice. (shrink)

The distribution of cultural variants in a population is shaped by both neutral evolutionary dynamics and by selection pressures. The temporal dynamics of social network connectivity, that is, the order in which individuals in a population interact with each other, has been largely unexplored. In this paper, we investigate how, in a fully connected social network, connectivity dynamics, alone and in interaction with different cognitive biases, affect the evolution of cultural variants. Using agent‐based computer simulations, we manipulate population connectivity dynamics (...) (early, mid, and late full‐population connectivity); content bias, or a preference for high‐quality variants; coordination bias, or whether agents tend to use self‐produced variants (egocentric bias), or to switch to variants observed in others (allocentric bias); and memory size, or the number of items that agents can store in their memory. We show that connectivity dynamics affect the time‐course of variant spread, with lower connectivity slowing down convergence of the population onto a single cultural variant. We also show that, compared to a neutral evolutionary model, content bias accelerates convergence and amplifies the effects of connectivity dynamics, while larger memory size and coordination bias, especially egocentric bias, slow down convergence. Furthermore, connectivity dynamics affect the frequency of high‐quality variants (adaptiveness), with late connectivity populations showing bursts of rapid change in adaptiveness followed by periods of relatively slower change, and early connectivity populations following a single‐peak evolutionary dynamic. We evaluate our simulations against existing data collected from previous experiments and show how our model reproduces the empirical patterns of convergence. (shrink)

This paper addresses the phenomenon of incomplete preferences in disaster risk management. If an agent finds two options to be incomparable and thus has an incomplete preference ordering, i.e., neither prefers one option over the other nor finds them equally as good, it is not possible for the agent to perform a value tradeoff, necessary for an informed decision, between these two options. In this paper we suggest a way to model incomplete preference orderings by means of probabilistic preferences, and (...) how to reveal an agent’s incomplete preference ordering within a behaviorist framework. (shrink)

While we cannot directly measure the psychological preferences of individuals, and the moral, emotional, and cognitive tendencies of people from the past, we can use cultural artifacts as a window to the zeitgeist of societies in particular historical periods. At present, an increasing number of digitized texts spanning several centuries is available for a computerized analysis. In addition, developments form historical economics have enabled increasingly precise estimations of sociodemographic realities from the past. Crossing these datasets offer a powerful tool to (...) test how the environment changes psychology and vice versa. However, designing the appropriate proxies of relevant psychological constructs is not trivial. The gold standard to measure psychological constructs in modern texts – Linguistic Inquiry and Word Count – has been validated by psychometric experimentation with modern participants. However, as a tool to investigate the psychology of the past, the LIWC is limited in two main aspects: it does not cover the entire range of relevant psychological dimensions and the meaning, spelling, and pragmatic use of certain words depend on the historical period from which the fiction work is sampled. These LIWC limitations make the design of custom tools inevitable. However, without psychometric validation, there is uncertainty regarding what exactly is being measured. To overcome these pitfalls, we suggest several internal and external validation procedures, to be conducted prior to diachronic analyses. First, the semantic adequacy of search terms in bags-of-words approaches should be verified by training semantic vector spaces with the historical text corpus using tools like word2vec. Second, we propose factor analyses to evaluate the internal consistency between distinct bag-of-words proxying the same underlying psychological construct. Third, these proxies can be externally validated using prior knowledge on the differences between genres or other literary dimensions. Finally, while LIWC is limited in the analysis of historical documents, it can be used as a sanity check for external validation of custom measures. This procedure allows a robust estimation of psychological constructs and how they change throughout history. Together with historical economics, it also increases our power in testing the relationship between environmental change and the expression of psychological traits from the past. (shrink)

Is there such a sub-discipline as “sociology of valuation and evaluation”? Identifying the main focus, the topics, and the analytical designs, i.e., reflecting on a theoretical profile of such an investigation, is far from complete. The main question is indeed—where to start when addressing the sociology of valuation and evaluation? Is it a specific area of research, analysis, and inquiry, with specific objects? Should we confine it to the many important qualitative and quantitative studies dedicated to the measure of market (...) performance, the efficiency of public policy, profitability of private investment, or identification of best practices in various areas ? Beyond business and administration processes, a huge body of research in economic sociology has developed in recent years that has renewed the investigations on economic experience through a moral lens (Lamont 2000; Vatin 2008; Karpik 2010; Beckert and Aspe .. (shrink)

There is widespread agreement in neuroscience and psychology that the visual system identifies objects and faces based on a pattern of activation over many neurons, each neuron being involved in representing many different categories. The hypothesis that the visual system includes finely tuned neurons for specific objects or faces for the sake of identification, so‐called “grandmother cells”, is widely rejected. Here it is argued that the rejection of grandmother cells is premature. Grandmother cells constitute a hypothesis of how familiar visual (...) categories are identified, but the primary evidence against this hypothesis comes from studies that have failed to observe neurons that selectively respond to unfamiliar stimuli. These findings are reviewed and it is shown that they are irrelevant. Neuroscientists need to better understand existing models of face and object identification that include grandmother cells and then compare the selectivity of these units with single neurons responding to stimuli that can be identified. (shrink)

Pour le bicentenaire conjoint des naissances de George Sand (1804-1876) et d’Agricol Perdiguier (1805-1876), Michèle Hecquet et Martine Watrelot ont eu l’heureuse initiative d’organiser à l’université de Lille 3, en décembre 2005, deux journées d’étude consacrées à l’analyse du Compagnon du Tour de France (1840), roman de G. Sand que l’on sait largement inspiré de la vie d’Agricol Perdiguier, compagnon menuisier, et de son Livre du compagnonnage (1839). Le résultat laisse un sentiment mitigé,...

Throughout the biological and biomedical sciences there is a growing need for, prescriptive ‘minimum information’ (MI) checklists specifying the key information to include when reporting experimental results are beginning to find favor with experimentalists, analysts, publishers and funders alike. Such checklists aim to ensure that methods, data, analyses and results are described to a level sufficient to support the unambiguous interpretation, sophisticated search, reanalysis and experimental corroboration and reuse of data sets, facilitating the extraction of maximum value from data sets (...) them. However, such ‘minimum information’ MI checklists are usually developed independently by groups working within representatives of particular biologically- or technologically-delineated domains. Consequently, an overview of the full range of checklists can be difficult to establish without intensive searching, and even tracking thetheir individual evolution of single checklists may be a non-trivial exercise. Checklists are also inevitably partially redundant when measured one against another, and where they overlap is far from straightforward. Furthermore, conflicts in scope and arbitrary decisions on wording and sub-structuring make integration difficult. This presents inhibit their use in combination. Overall, these issues present significant difficulties for the users of checklists, especially those in areas such as systems biology, who routinely combine information from multiple biological domains and technology platforms. To address all of the above, we present MIBBI (Minimum Information for Biological and Biomedical Investigations); a web-based communal resource for such checklists, designed to act as a ‘one-stop shop’ for those exploring the range of extant checklist projects, and to foster collaborative, integrative development and ultimately promote gradual integration of checklists. (shrink)

A long tradition of research in WEIRD (Western, Educated, Industrialized, Rich, Democratic) countries has investigated how people weigh individual welfare versus group welfare in their moral judgments. Relatively less research has investigated the generalizability of results across non-WEIRD populations. In the current study, we ask participants across nine diverse cultures (Bali, Costa Rica, France, Guatemala, Japan, Madagascar, Mongolia, Serbia, and the USA) to make a series of moral judgments regarding both third-party sacrifice for group welfare and first-person sacrifice for group (...) welfare. In addition to finding some amount of cross-cultural variation on most of our questions, we also find two cross-culturally consistent judgments: (1) when indi- viduals are in equivalent situations, overall welfare should be maximized, and (2) harm to individuals should be taken into account, and some types of individual harm can trump overall group welfare. We end by discussing the specific pattern of variable and consistent features in the context of evolutionary theories of the evolution of morality. (shrink)

After reviewing the literature on current knowledge about consciousness in humans, we present a state-of-the art discussion on consciousness and related key concepts in animals. Obviously much fewer publications are available on non-human species than on humans, most of them relating to laboratory or wild animal species, and only few to livestock species. Human consciousness is by definition subjective and private. Animal consciousness is usually assessed through behavioural performance. Behaviour involves a wide array of cognitive processes that have to be (...) assessed separately using specific experimental protocols. Accordingly, several processes indicative of the presence of consciousness are discussed: perception and cognition, awareness of the bodily-self, self-related knowledge of the environment (including social environment). When available, specific examples are given in livestock species. Next, we review the existing evidence regarding neuronal correlates of consciousness, and emphasize the difficulty of linking aspects of consciousness to specific neural structures across the phyla because high-level cognitive abilities may have evolved independently along evolution. Several mammalian brain structures (cortex and midbrain) are involved in the manifestations of consciousness, while the equivalent functional structures for birds and fishes would likely be the pallium/tectum and midbrain. Caution is required before excluding consciousness in species not having the same brain structures as the mammalian ones as different neural architectures may mediate comparable processes. Finally, specific neurophysiological mechanisms appear to be strongly linked to the emergence of consciousness, namely neural synchrony and neural feedback. Considering the limited amount of data available and the few animal species studied so far, we conclude that different manifestations of consciousness can be observed in animals but that further refinement is still needed to characterize their level and content in each species. Further research is required to clarify these issues, especially in livestock species. (shrink)

This book highlights some of the most pressing safety, ethical, legal and societal issues related to the diverse contexts in which robotic technologies apply. Focusing on the essential concept of well-being, it addresses topics that are fundamental not only for research, but also for industry and end-users, discussing the challenges in a wide variety of applications, including domestic robots, autonomous manufacturing, personal care robots and drones.